منابع مشابه
Gene Family: Structure, Organization and Evolution
Gene families are considered as groups of homologous genes which they share very similar sequences and they may have identical functions. Members of gene families may be found in tandem repeats or interspersed through the genome. These sequences are copies of the ancestral genes which have underwent changes. The multiple copies of each gene in a family were constructed based on gene duplicati...
متن کاملPredict protein structure through evolution
* 1 CUBIC, Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168 Street BB217, New York, NY 10032, USA; 2 Columbia University Center for Computational Biology and Bioinformatics (C2B2), Russ Berrie Pavilion, 1150 St. Nicholas Avenue, New York, NY 10032, USA; 3 North East Structural Genomics Consortium (NESG), Department of Biochemistry and Molecular Biophysics, ...
متن کاملEvolution Studied Using Protein Structure
One of the principle goals of evolutionary biology is to generate phylogeny that best represents the evolutionary histories of all organisms on earth. Aside from directly investigating the fossil records of ancestor species, all phylogenetic methods depend on the comparison of specific features (homologous characteristics) of contemporary organisms to determine the evolutionary relationships be...
متن کاملCombining protein evolution and secondary structure.
An evolutionary model that combines protein secondary structure and amino acid replacement is introduced. It allows likelihood analysis of aligned protein sequences and does not require the underlying secondary (or tertiary) structures of these sequences to be known. One component of the model describes the organization of secondary structure along a protein sequence and another specifies the e...
متن کاملGene3D: modelling protein structure, function and evolution
The Gene3D release 4 database and web portal (http://cathwww.biochem.ucl.ac.uk:8080/Gene3D) provide a combined structural, functional and evolutionary view of the protein world. It is focussed on providing structural annotation for protein sequences without structural representatives--including the complete proteome sets of over 240 different species. The protein sequences have also been cluste...
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ژورنال
عنوان ژورنال: Evolution
سال: 1978
ISSN: 0014-3820
DOI: 10.1111/j.1558-5646.1978.tb01118.x